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TECHNOLOGY

Overview
CombiPhos Catalysts were derived from novel combinatorial technologies, and used for a variety of cross-coupling reactions. So far, over 900 pharmaceutical companies over the world apply these catalysts in the drug discovery and processes. Among these pharmaceutical companies are Pfizer, Merck, Novartis, GSK, Sanofi Aventis, AstraZeneca, J&J, BMS, Abbvie, Eli Lilly, Amgen, Gilead, Takeda, Celgene, Genentech, Biogen Idec, Boehringer Ingelheim, Bayer, Lundbeck, Vertex, Roche, etc.
Four Advantages of CombiPhos' Cross-Coupling Catalysts
  1. Air- and Moisture-Stability (can be stored in air for many years, and use H2O as a solvent!).
  2. Very High Activity [about 100 times higher than other catalysts (e.g. Pd(PPh3)4, PdCl2(dppf) etc !).
  3. Catalyst Residue can be easily removed (residue is an ionic complex which is less soluble in organic solvents !).
  4. Catalyst is recyclable (can be re-used for many times !)
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